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KMID : 1130620120080040276
Journal of Clinical Neurology
2012 Volume.8 No. 4 p.276 ~ p.283
Validation of the Korean-Version of the Nonmotor Symptoms Scale for Parkinson¡¯s Disease
Koh Seong-Beom

Kim Jae-Woo
Ma Hyeo-Il
Ahn Tae-Beom
Cho Jin-Whan
Lee Phil-Hyu
Chung Sun-Ju
Kim Joong-Seok
Kwon Do-Young
Baik Jong-Sam
Abstract
Background and Purpose: Non-motor symptoms are common in Parkinson¡¯s disease (PD), and are the primary cause of disability in many PD patients. Our aim in this study was to translate the origin non-motor symptoms scale for PD (NMSS), which was written in English, into Korean (K-NMSS), and to evaluate its reliability and validity for use with Korean-speaking patients with PD.

Methods: In total, 102 patients with PD from 9 movement disorders sections of university teaching hospitals in Korea were enrolled in this study. They were assessed using the K-NMSS, the Unified Parkinson¡¯s Disease Rating Scale (UPDRS), the Korean version of the Mini-Mental Status Examination (K-MMSE), the Korean version of the Montgomery-Asberg Depression Rating Scale (K-MADS), the Epworth Sleepiness Scale (ESS), and Parkinson¡¯s Disease Questionnaire 39 (PDQ39). Test-retest reliability was assessed over a time interval of 10-14 days in all but one patient.

Results: The K-NMSS was administered to 102 patients with PD. The internal consistency and reliability of this tool was 0.742 (mean Cronbach¡¯s ¥á-coefficient). The test-retest correlation reliability was 0.941 (Guttman split-half coefficient). There was a moderate correlation between the total K-NMSS score and the scores for UPDRS part I [Spearman¡¯s rank correlation coefficient, (rS)=0.521, p<0.001] and UPDRS part II (rS=0.464, p=0.001), but there was only a weak correlation between the total K-NMSS score and the UPDRS part III score (rS=0.288, p=0.003). The total K-NMSS score was significantly correlated with the K-MADS (rS=0.594, p<0.001), KMMSE (rS=-0.291, p=0.003), and ESS (rS=0.348, p<0.001). The total K-NMSS score was also significantly and positively correlated with the PDQ39 score (rS=0.814, p<0.001).

Conclusions: The K-NMSS exhibited good reliability and validity for the assessment of nonmotor symptoms in Korean PD patients.
KEYWORD
Parkinson¡¯s disease, non-motor symptoms scale, validation
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